The Optometry and Ophthalmology department are involved in various research projects.
The following studies are in progress or due to start shortly:
ASTUTE study – Research into Adalimumab vs a placebo as an add-on to Standard Therapy for autoimmune Uveitis. Members of the Optometry team are certified Investigators of Visual Acuity measurement
CHROMEOS study – Research into the genetics of Achromatopsia. Members of the Optometry team are certified Investigators of Visual Acuity measurement
COAST study- Research comparing single or combination Intravitreal therapies for nAMD. Members of the Optometry team are certified Investigators of Visual Acuity measurement
GALE study – Research into the long term effects of Intra vitreal treatment (IVT) in Geographic Atrophy (dry AMD). Members of the Optometry team are certified Investigators of Visual Acuity measurement
MEIRA (010) study – Research into the long term effects of patients having Gene therapy for X-linked Retinitis Pigmentosa. Members of the Optometry team are certified Investigators of Visual Acuity measurement
PARADIGM study – Research into the ocular effects of treatment vs. placebo for Osteoarthritis knee pain. Members of the Optometry team are certified Investigators of Visual Acuity measurement
PRECISE study – Research using Artificial intelligence to analyse scans to predict response to IVT for nAMD. Members of the Optometry team are certified Investigators of Visual Acuity measurement
All of the following studies have either closed or are close to closing (closed to recruitment).
DERBY study – Research into drug therapy for patients with Non exudative (dry) maculopathy. Members of the Optometry team are certified Investigators of Visual Acuity measurement
MATE study – Research into drug therapy for patients with Exudative (wet) maculopathy using the drug Aflibercept as standard treatment versus treat and extend. Members of the Optometry team are certified Investigators of Visual Acuity measurement
PANDA study – Research into drug therapy for patients with Exudative (wet) maculopathy. Members of the Optometry team are certified Investigators of Visual Acuity measurement
RAVEN study – Research into drug therapy for patients with Macular oedema due to Branch Retinal Vein Occlusion. Members of the Optometry team are certified Investigators of Visual Acuity measurement
RHINE study – Research into drug therapy for patients with Diabetic Macular Oedema. Members of the Optometry team are certified Investigators of Visual Acuity measurement
SCOPE study – Research into drug therapy for patients with Non exudative (dry) maculopathy. Members of the Optometry team are certified Investigators of Visual Acuity measurement
TENAYA study – Research into drug therapy for patients with Exudative (wet) maculopathy. Members of the Optometry team are certified Investigators of Visual Acuity measurement
THROMBO study – Research into drug therapy for patients with Diabetic Macular Oedema. Members of the Optometry team are certified Investigators of Visual Acuity measurement
VICI study – Research into drug therapy for patients with Central Serous Retinopathy. Members of the Optometry team are certified Investigators of Visual Acuity measurement
XOLARIS study – Research into Retinitis Pigmentosa. Members of the Optometry team are certified Investigators of Microperimetry, Visual Acuity and Contrast Sensitivity measurement.
Previous research has included:
Research into the use of tinted spectacles for retinal dystrophies
Research into drug therapy for Exudative (wet) Macular degeneration with:
Aflibercept – members of the Optometry team are certified Investigators of Visual Acuity measurement
Anecortave Acetate – members of the Optometry team are Phase 3 Trial Certified Investigators of Visual Acuity and Contrast Sensitivity measurement
Macugen – members of the Optometry team are Investigators of Visual Acuity and Contrast Sensitivity measurement
Lucentis – members of the Optometry team are certified Investigators of Visual Acuity measurement
Research into drug therapy for Cystoid Macular Degeneration with:
Posurdex – members of the Optometry team are EMMES certified Investigators of Visual Acuity and Contrast Sensitivity
Lucentis versus Eylea versus Avastin – members of the Optometry team are certified Investigators of Visual Acuity measurement
Research into refractive and corneal surgery in conjunction with the External Link St. James’s LaserVision centre based at St. James’s University Hospital.
Research into drug therapy for diabetic retinopathy with:
Aflibercept – members of the Optometry team are certified Investigators of Visual Acuity measurement