Haptoglobin is a serum glycoprotein which binds free haemoglobin. The haptoglobin-Hb complex is cleared by the reticuloendothelial system. Haptoglobin is depleted from serum in states of intravascular haemolysis. Haptoglobin rises as part of the acute phase response.
Tube
Serum gel
ID
12766
Availability
Weekdays
Additional Information
Haptoglobin is an “acute-phase” protein; this means that it will be increased in many inflammatory diseases such as ulcerative colitis, acute rheumatic disease, heart attack and severe infection. This can complicate the interpretation of the haptoglobin results. Haptoglobin testing is not used to help diagnose or monitor these conditions. Haptoglobin levels may be affected by massive blood loss and by conditions associated with kidney dysfunction, as well as liver disease. Drugs that can increase haptoglobin levels include androgens and corticosteroids such as prednisolone. Drugs that can decrease haptoglobin concentrations include isoniazid, quinidine, streptomycin and birth control pills. [Source of information: Lab Tests Online]
Turn around
7 days
Send to
Leeds General Infirmary
Clinical Immunology
Old Medical School
Great George Street
Leeds
LS1 3EX
Collection Con
No restrictions
Frequency
Weekdays
Sample REQ
Blood
Ref. Range (Male)
0.5 – 2.0
Ref. Range (Female)
0.4 – 1.6
Units
g/L
IP Acute TAT
Contact Laboratory
IP Routine TAT
7 days
GP Acute TAT
Contact Laboratory
GP Routine TAT
7 days